The annual report of cancer trends of the American Cancer Association revealed a mix of news and statistics for 2025.
The rate of cancer death has dropped 34% between 1991 and 2022, which ACS attributes early detection, decreasing smoking and improvements in treatment.
While these numbers are encouraging, oncologists and cancer specialists still have concerns about several other factors.
While the report shows constant progress on many fronts, certain areas remain of “important concern”, Dr. Joshua Strauss, a hematologist and medical oncologist in advanced oncology and Atlantic medical hematology associates in Morristown, New Jersey, with Fox News Digital.
Below are some of the most worrying trends, according to experts.
1. Cancer deaths that do not improve in new individuals
The prevalence of cancer in young individuals and adolescents has continued to increase, according to the report, with adolescence rates that grow slowly by 0.7% each year.
Cancer is the leading cause of death in children and adolescents-often leukemia, brain cancer and lymphoma.
In 2025, ACS estimates that 9,550 children to 14 years and 5,140 teens aged 15 to 19 will be diagnosed with cancer, and that 1,050 children and 600 teens will die.
Dr. Paul Oberstein, a gastrointestinal medical oncologist and chief of the GI medical oncology section at the NYU Langone Perlmutter Cancer Center, reiterated that people under the age of 50 are seeing higher levels of cancer deaths.
“It is shown in numerous cancers,” he told Fox News Digital. “I would say the biggest finding is in young women with breast cancer.”
The prevalence of GI cancers (gastrointestinal) is also increasing among young adults, including pancreatic and colon cancer.
Experts have different hypotheses as to why young people are being diagnosed more often, including diet, microplasty exposure or other environmental causes, according to Oberstein.
“We don’t have a good explanation and we need to invest to find out why it can happen so so we can change it,” he said.
2. Cervical cancer continues to pose unnecessary threat
Cervical cancer is one of the few cancers that can be prevented, however thousands of women are still at risk.
While the incidence level of cervical cancer decreased by more than half from the mid -1970s to the mid -2000s due to the review, these numbers have stabilized since then, according to the report.
A 13,000 predicted women will be diagnosed with cervical cancer in 2025 and 4,000 will die, according to Dr. Jessica Shepherd, an obstetrician gynecologist certified by the Board in Dallas, Texas.
“Cervical cancer in women from 30 to 44 is increasing,” she told Fox News Digital. “But also, this is a cancer that has the potential to disappear if it is not eliminated, due to us knowing understanding HPV and its spread to the disease.”
HPV (human papillomavirus infection), the most common cause of cervical cancer, can be detected through testing.
“We have innovations and technology that needs to lower some levels of cervical cancer,” Shepherd said.
3 Some communities lack healthcare access
The ACS report found that local Americans and black people continue to die at higher rates than white people for several different cancers.
Among patients with cervical cancer, the death rate in black women and local women is 50% and 70% higher than in white women.
The five-year relative survival rate for cervical cancer in black women is 58% compared to 67% of white women, the report revealed.
This mismatch in the mortality rate is most likely due to lack of access to doctors and regular performances, added Shepherd, who pushed for more research, awareness and public education.
“Cervical cancer is preventable through examination with PAP plus HPV and co-testing,” she said. “If we had the ability to have more early early detection, then we can see abnormalities in cells … before dealing with cancer and could take the time to address it.”
4. GI cancer diagnostics are deteriorating
Gastrointestinal cancers (GI), such as pancreatic, liver, colorectal and stomach cancers, are all considered very deadly.
The ACS report noted that colorectal diagnoses in men and women under the age of 65 have continued to grow.
Between 2012 and 2021, the incidence of colorectal cancer increased by 2.4% each year in people younger than 50 and 0.4% per year in adults 50 to 64.
Pancreas cancer progress is also pursuing other cancers, according to the report, as the level of incidence and mortality increases by 1% each year in men and women.
ACS noted that in 2025, about 67,440 new cases of pancreatic cancer will be diagnosed in the US and 51,980 people will die from it.
The rate of death for pancreatic cancer has increased by 0.2% to 0.3% each year in men and women, and the five-year relative survival rate is 13%, which Strauss described as “shameful”.
Oberstein, a GI specialist, noted that these types of cancers “often have very poor results”, although there have been some improvements in early detection and treatment in recent decades.
“The biggest benefit we have seen to mortality comes from the previous discovery of GI cancers,” he told Fox News Digital, adding that colon cancer has the best results when detected early.
“But we really need to double in trying to detect gastric cancer, liver cancer and especially pancreatic cancer earlier in order to make a big difference,” Oberstein said.
Melissa Rudy of Fox News Digital contributed to this report.
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