How much weight loss while obese can make you more likely to die

Can loss of weight mean loss of life?

New research shows that even extreme weight loss and weight gain significantly increase the risk of death in obese individuals with heart disease.

The American Heart Association warns that 61% of American adults are likely to have a type of heart disease in the next 30 years as high blood pressure, diabetes and overweight become more common.

In this latest study, researchers at England University of England analyzed data from 8,297 stupid people through the UK Boobank.


Thick woman undergoing cardiovascular fitness evaluation in a routine, monitored by a health care professional with electrodes attached to her chest
The American Heart Association warns that 61% of American adults are likely to have a kind of cardiovascular disease in the next 30 years. Bgstock72 – stock.adobe.com

Cardiovascular disease refers to some conditions, including heart attack, heart failure, heart arrhythmias, vascular disease, congenital heart defects, stroke and high blood pressure.

It has been the main cause of death in the US since AHA was founded in 1924, while the blow is the fifth cause of death.

Publishing in the Heart magazine, researchers found that compared to those holding their weight, patients who lost more than 22 pounds during the study increased their risk of mortality of all causes by 54%.

In contrast, those who gained more than 22 pounds during that time almost doubled their risk for everyone causing mortality and increased their risk of cardiovascular death for three times.

According to the team, these results suggest that weight fluctuations in each extreme are harmful to overall health.

“Keeping a stable weight, even within the thick range, seems to be essential for reducing the risk of mortality in patients with cardiovascular disease,” said the main author Dr. Jefen Zhang.

“It was probably surprising that significant weight gain was associated with higher but interesting mortality that a similar association was found among those who lost a lot of weight.”

Recent preliminary research has found that survivors in the brain can significantly reduce their risk of another stroke, a heart attack or premature death by taking GLP-1 drugs such as Ozepic or Jardiance. WEGOVY, meanwhile, has been shown to reduce the overall risk of heart attack and stroke.

Zhang and his team found a link between significant weight gain and high body mass index, smoking, alcohol consumption and younger age.


Overweight woman measuring waist, expressing the desire to lose weight for health
The people of overweight and obese under 25 increased from 198 million to 493 million between 1990 and 2021. This number is projected to reach 746 million by 2050. Charlie’s – Stock.adobe.com

A 2024 study predicts that about 60% of adults and nearly one -third of young people worldwide will be overweight or overweight by 2050.

The people of overweight and obese under 25 increased from 198 million to 493 million between 1990 and 2021. This number is projected to reach 746 million by 2050.

While GLP-1 drugs like Ozepic and Wegovy have been greeted as a miracle cure for overweight, Zhang wants providers and patients to be aware of the potential risks of losing weight quickly.

“This study is the first of its kind to examine the link between weight change and mortality of all causes in thick individuals with cardiovascular disease,” he said. “Clinics should keep in mind this, especially in terms of new medicines in the market, which are praised for providing rapid weight loss.”

He noted that while weight loss is recommended for thick adults, risk groups, including those with history of cardiovascular disease should consult and collaborate with a medical professional to safely scaling their weight loss.

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